COVID-19 in pregnant women: a comparative observational study of pregnancy outcome in three waves of COVID-19 in district hospital, Ballari

Authors

  • Suyajna D. Joshi Department of Obstetrics and Gynecology, District Hospital, Ballari, Karnataka, India
  • Vijayalakshmi G. Department of Obstetrics and Gynecology, District Hospital, Ballari, Karnataka, India
  • Ruksar Banu Department of Obstetrics and Gynecology, District Hospital, Ballari, Karnataka, India
  • Jayasakthi G. Department of Obstetrics and Gynecology, District Hospital, Ballari, Karnataka, India
  • Shrilakshmi R. A. Department of Obstetrics and Gynecology, District Hospital, Ballari, Karnataka, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20223488

Keywords:

Coronavirus, COVID-19, Pandemic, Pneumonia, Pregnant women, SARS-CoV-2

Abstract

Background: A three wave pattern of corona virus has been seen in many countries during the 2020 pandemic. Observed data show that the effects of the virus do vary between the three waves. Differences in severity of the disease have been reported, although the comparative characteristics of the three waves still remain largely unknown.

Methods: This was a prospective cross sectional study continuation of our first paper comparing 133 pregnant COVID- 19 positive patients in the first wave and 251 patients admitted during second wave and 92 patients in third wave who delivered at district hospital, Bellary.

Results: In the present study 72.8% patients were in the age of 20-30 years, 85.87% patients belong to lower socio- economic status, mild anaemia about 32.6% in third wave, moderate anaemia seen in 10.8% in third wave, and 3.44% had severe anaemia. Non-severe pre-eclampsia was present in 10.8% of the patients, severe pre-eclampsia was seen in 6.52% of the cases and. Mode of delivery was 29.34% FTND, 3.26% FTVD emergency LSCS was 63.06% in third wave, and preterm delivery was seen in 4.34% in third wave. Elevated levels of D-dimer were found 25% in third wave. 0 deaths being reported in third wave.

Conclusions: This study compared the obstetric and clinical outcome in COVID-19 positive patients who are in labor in first, second, and third wave of COVID-19 infection. Although our conclusions are limited, the finding so obtained are important for understanding the clinical parameters, obstetric parameters and perinatal outcome in three waves.

References

Wang C, Horby PW, Hayden FG, Gao GF. A novel coronavirus outbreak of global health concern. Lancet. 2020;395(10223):470-3.

Sokolovska L, Sultanova A, Cistjakovs M. COVID-19: The third wave of coronavirus infection outbreak. J Transl Sci. 2020.

Richman DD, Whitley RJ, Hayden FG. Clinical Virology. 4th ed. Washington: ASM Press; 2016.

Memish ZA, Perlman S, Van Kerkhove MD, Zumla A. Middle East respiratory syndrome. Lancet. 2020;395(10229):1063-77.

Rothe C, Schunk M, Sothmann P. Transmission of 2019-nCoV infection from an asymptomatic contact in Germany. N Engl J Med. 2020;382:970-1.

Cheng ZJ, Shan J. 2019 novel coronavirus: where we are and what we know. Infection. 2020;48:155-63.

Chen H, Guo J, Wang C. Clinical characteristics and intrauterine vertical transmission potential of COVID- 19 infection in nine pregnant women: a retrospective study. J Transl Sci. 2019;23:121-8.

Wong SF, Chow KM, Leung TN. Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. Am J Obstet Gynecol. 2004; 191:292-7.

Suyajna JD, Vijayalakshmi G, Kavya A. Severe acute respiratory syndrome corona virus 2 in pregnant women: an observational study. Int J Reprod Contracept Obstet Gynecol. 2020;9(12): 4892-7.

Coronaviridae Study Group of the international committee on taxonomy of viruses. The species severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nat Microbiol. 2018;23:45-9.

Cui J, Li F, Shi ZL. Origin and evolution of pathogenic coronaviruses. Nat Rev Microbiol. 2019; 7:181-92.

Kotwal A, Yadav AK, Pareek A. Saga of COVID 19: Focus on third and subsequent waves. CMRP. 2022;117:138-45.

Coronavirus Outbreak in India. Available at: https://www.covid19india.org/state/TT. Accessed on 20 July 2021.

Kumar A. Characterizing the third wave of COVID-19: an analysis from the National clinical registry of COVID-19. Indian J Med Res. 2022;10:276.

Downloads

Published

2022-12-28

Issue

Section

Original Research Articles