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Case report
Intravenous immunoglobulin in COVID-19 associated Guillain–Barré syndrome in pregnancy
  1. Jao Jarro Garcia,
  2. Christian Wilson Turalde,
  3. Marjorie Anne Bagnas and
  4. Veeda Michelle Anlacan
  1. Department of Neurosciences, Philippine General Hospital, Manila, Philippines
  1. Correspondence to Dr Jao Jarro Garcia; jbgarcia14{at}up.edu.ph

Abstract

The COVID-19 pandemic has led to a rise in cases of Guillain-Barré syndrome (GBS). This autoimmune sequela is a manifestation of the neurotropism potential of the virus. At present, knowledge regarding the pathophysiology, clinical features, management and outcomes of the condition is still evolving. This paper presents the case of a 22-year-old pregnant patient who came in with a history of upper respiratory tract symptoms followed by acroparaesthesia and progressive ascending weakness. She was confirmed to have COVID-19 and GBS and was subsequently managed with intravenous immunoglobulin (IVIg) followed by supportive therapy. To the authors’ knowledge and based on their literature search, this is the first reported case of GBS in a COVID-19 confirmed pregnant patient who received IVIg.

  • neurology
  • peripheral nerve disease
  • pregnancy

This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.

https://bmj.com/coronavirus/usage

https://doi.org/10.1136/bcr-2021-242365

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    Footnotes

    • Twitter @WilsonTuralde

    • Contributors JJG: conceptualisation, literature review, manuscript writing, manuscript editing. CWT and VMA: conceptualisation, manuscript review and editing. MAB: performance and analysis of electrodiagnostic test, manuscript review and editing.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.