Profile of laboratory tests of patients admitted to an Intensive Care Unit (ICU) with severe forms of COVID-19

Authors

DOI:

https://doi.org/10.33448/rsd-v11i16.38199

Keywords:

ICU; COVID-19; Comorbidities; Lab diagnosis.

Abstract

SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus) is the etiological agent responsible for the development of coronavirus disease (COVID-19). Which is a disease that affects the airways, and most often can cause pneumonia. Despite the viral origin, antimicrobial drugs are often prescribed, so that about 15% of patients with SARS-CoV-2 have a secondary infection caused by bacteria, which explains the antibiotic treatment. These drugs, when prescribed regardless of the existence of a bacterial infection, can lead to possible bacterial resistance. The objective of this work is to analyze the profile of laboratory tests of patients admitted to an ICU with severe forms of COVID-19, in a private hospital in a city in the southwestern region of Bahia. This is a documental study, with primary data source. The approach is quantitative, descriptive, exploratory, and cross-sectional, through data survey. Among the 52 medical records evaluated, it was possible to observe that the male gender had a higher rate of hospitalization and most of them were elderly. It is possible to observe an increase in the number of leukocytes and platelets after antibiotic therapy. And in relation to CRP, the value was significantly reduced after the administration of antimicrobial drugs. According to the analysis of the laboratory results, it was possible to observe that there were important alterations in the infection markers, which may be related to the use of antimicrobial drugs.

Author Biographies

Nattan Rangel Fernandes Moura , Faculdade Independente do Nordeste

SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus) is the etiological agent responsible for the development of coronavirus disease (COVID-19). Which is a disease that affects the airways, and most often can cause pneumonia. Despite the viral origin, antimicrobial drugs are often prescribed, so that about 15% of patients with SARS-CoV-2 have a secondary infection caused by bacteria, which explains the antibiotic treatment. These drugs, when prescribed regardless of the existence of a bacterial infection, can lead to possible bacterial resistance. The objective of this work is to analyze the profile of laboratory tests of patients admitted to an ICU with severe forms of COVID-19, in a private hospital in a city in the southwestern region of Bahia. This is a documental study, with primary data source. The approach is quantitative, descriptive, exploratory, and cross-sectional, through data survey. Among the 52 medical records evaluated, it was possible to observe that the male gender had a higher rate of hospitalization and most of them were elderly. It is possible to observe an increase in the number of leukocytes and platelets after antibiotic therapy. And in relation to CRP, the value was significantly reduced after the administration of antimicrobial drugs. According to the analysis of the laboratory results, it was possible to observe that there were important alterations in the infection markers, which may be related to the use of antimicrobial drugs

Glenda Farias Pierote, Faculdade Independente do Nordeste

SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus) is the etiological agent responsible for the development of coronavirus disease (COVID-19). Which is a disease that affects the airways, and most often can cause pneumonia. Despite the viral origin, antimicrobial drugs are often prescribed, so that about 15% of patients with SARS-CoV-2 have a secondary infection caused by bacteria, which explains the antibiotic treatment. These drugs, when prescribed regardless of the existence of a bacterial infection, can lead to possible bacterial resistance. The objective of this work is to analyze the profile of laboratory tests of patients admitted to an ICU with severe forms of COVID-19, in a private hospital in a city in the southwestern region of Bahia. This is a documental study, with primary data source. The approach is quantitative, descriptive, exploratory, and cross-sectional, through data survey. Among the 52 medical records evaluated, it was possible to observe that the male gender had a higher rate of hospitalization and most of them were elderly. It is possible to observe an increase in the number of leukocytes and platelets after antibiotic therapy. And in relation to CRP, the value was significantly reduced after the administration of antimicrobial drugs. According to the analysis of the laboratory results, it was possible to observe that there were important alterations in the infection markers, which may be related to the use of antimicrobial drugs.

 

Natiele Ramos Silva, Faculdade Independente do Nordeste

SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus) is the etiological agent responsible for the development of coronavirus disease (COVID-19). Which is a disease that affects the airways, and most often can cause pneumonia. Despite the viral origin, antimicrobial drugs are often prescribed, so that about 15% of patients with SARS-CoV-2 have a secondary infection caused by bacteria, which explains the antibiotic treatment. These drugs, when prescribed regardless of the existence of a bacterial infection, can lead to possible bacterial resistance. The objective of this work is to analyze the profile of laboratory tests of patients admitted to an ICU with severe forms of COVID-19, in a private hospital in a city in the southwestern region of Bahia. This is a documental study, with primary data source. The approach is quantitative, descriptive, exploratory, and cross-sectional, through data survey. Among the 52 medical records evaluated, it was possible to observe that the male gender had a higher rate of hospitalization and most of them were elderly. It is possible to observe an increase in the number of leukocytes and platelets after antibiotic therapy. And in relation to CRP, the value was significantly reduced after the administration of antimicrobial drugs. According to the analysis of the laboratory results, it was possible to observe that there were important alterations in the infection markers, which may be related to the use of antimicrobial drugs.

 

Juliana Abreu Bacelar, Faculdade Independente do Nordeste

 

SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus) is the etiological agent responsible for the development of coronavirus disease (COVID-19). Which is a disease that affects the airways, and most often can cause pneumonia. Despite the viral origin, antimicrobial drugs are often prescribed, so that about 15% of patients with SARS-CoV-2 have a secondary infection caused by bacteria, which explains the antibiotic treatment. These drugs, when prescribed regardless of the existence of a bacterial infection, can lead to possible bacterial resistance. The objective of this work is to analyze the profile of laboratory tests of patients admitted to an ICU with severe forms of COVID-19, in a private hospital in a city in the southwestern region of Bahia. This is a documental study, with primary data source. The approach is quantitative, descriptive, exploratory, and cross-sectional, through data survey. Among the 52 medical records evaluated, it was possible to observe that the male gender had a higher rate of hospitalization and most of them were elderly. It is possible to observe an increase in the number of leukocytes and platelets after antibiotic therapy. And in relation to CRP, the value was significantly reduced after the administration of antimicrobial drugs. According to the analysis of the laboratory results, it was possible to observe that there were important alterations in the infection markers, which may be related to the use of antimicrobial drugs.

Maria Clara Costa Lacerda, Faculdade Independente do Nordeste

SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus) is the etiological agent responsible for the development of coronavirus disease (COVID-19). Which is a disease that affects the airways, and most often can cause pneumonia. Despite the viral origin, antimicrobial drugs are often prescribed, so that about 15% of patients with SARS-CoV-2 have a secondary infection caused by bacteria, which explains the antibiotic treatment. These drugs, when prescribed regardless of the existence of a bacterial infection, can lead to possible bacterial resistance. The objective of this work is to analyze the profile of laboratory tests of patients admitted to an ICU with severe forms of COVID-19, in a private hospital in a city in the southwestern region of Bahia. This is a documental study, with primary data source. The approach is quantitative, descriptive, exploratory, and cross-sectional, through data survey. Among the 52 medical records evaluated, it was possible to observe that the male gender had a higher rate of hospitalization and most of them were elderly. It is possible to observe an increase in the number of leukocytes and platelets after antibiotic therapy. And in relation to CRP, the value was significantly reduced after the administration of antimicrobial drugs. According to the analysis of the laboratory results, it was possible to observe that there were important alterations in the infection markers, which may be related to the use of antimicrobial drugs.

Tatielle Pereira Silva, Faculdade Independente do Nordeste

SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus) is the etiological agent responsible for the development of coronavirus disease (COVID-19). Which is a disease that affects the airways, and most often can cause pneumonia. Despite the viral origin, antimicrobial drugs are often prescribed, so that about 15% of patients with SARS-CoV-2 have a secondary infection caused by bacteria, which explains the antibiotic treatment. These drugs, when prescribed regardless of the existence of a bacterial infection, can lead to possible bacterial resistance. The objective of this work is to analyze the profile of laboratory tests of patients admitted to an ICU with severe forms of COVID-19, in a private hospital in a city in the southwestern region of Bahia. This is a documental study, with primary data source. The approach is quantitative, descriptive, exploratory, and cross-sectional, through data survey. Among the 52 medical records evaluated, it was possible to observe that the male gender had a higher rate of hospitalization and most of them were elderly. It is possible to observe an increase in the number of leukocytes and platelets after antibiotic therapy. And in relation to CRP, the value was significantly reduced after the administration of antimicrobial drugs. According to the analysis of the laboratory results, it was possible to observe that there were important alterations in the infection markers, which may be related to the use of antimicrobial drugs.

Aline Teixeira Amorim, Faculdade Independente do Nordeste

O SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus) é o agente etiológico responsável pelo desenvolvimento da doença do coronavírus (COVID-19). Que é uma doença que acomete as vias respiratórias, e na maior parte das vezes pode causar a pneumonia. Apesar da origem viral, frequentemente, são prescritos medicamentos antimicrobianos, sendo assim, cerca de 15% dos pacientes contagiados pelo SARS-CoV-2 apresentam um quadro de infecção secundária causada por bactérias, o que explica o tratamento com antibióticos. Esses fármacos, quando prescritos independentemente da existência de uma infecção causada por bactérias, podem acarretar em uma possível resistência bacteriana. O objetivo deste trabalho é analisar o perfil dos exames laboratoriais dos pacientes internados em uma UTI com formas graves da COVID-19, em um hospital privado de um município da região sudoeste da Bahia. Trata-se de um estudo de caráter documental, com fonte primária de dados. A abordagem é quantitativa de cunho descritivo, exploratório e de natureza transversal, por meio do levantamento de dados. Dentre os 52 prontuários avaliados, foi possível observar que o gênero masculino obteve uma maior taxa de internação e em sua maioria eram idosos. É possível observar um aumento do número de leucócitos e plaquetas, após a antibioticoterapia. E em relação a PCR, o valor foi significativamente reduzido, após a administração de fármacos antimicrobianos. De acordo com a análise dos resultados laboratoriais, foi possível observar que houveram alterações importantes nos marcadores de infecção, o que pode estar relacionado com uso dos antimicrobianos.

Fernanda Santos Portela, Faculdade Independente do Nordeste

SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus) is the etiological agent responsible for the development of coronavirus disease (COVID-19). Which is a disease that affects the airways, and most often can cause pneumonia. Despite the viral origin, antimicrobial drugs are often prescribed, so that about 15% of patients with SARS-CoV-2 have a secondary infection caused by bacteria, which explains the antibiotic treatment. These drugs, when prescribed regardless of the existence of a bacterial infection, can lead to possible bacterial resistance. The objective of this work is to analyze the profile of laboratory tests of patients admitted to an ICU with severe forms of COVID-19, in a private hospital in a city in the southwestern region of Bahia. This is a documental study, with primary data source. The approach is quantitative, descriptive, exploratory, and cross-sectional, through data survey. Among the 52 medical records evaluated, it was possible to observe that the male gender had a higher rate of hospitalization and most of them were elderly. It is possible to observe an increase in the number of leukocytes and platelets after antibiotic therapy. And in relation to CRP, the value was significantly reduced after the administration of antimicrobial drugs. According to the analysis of the laboratory results, it was possible to observe that there were important alterations in the infection markers, which may be related to the use of antimicrobial drugs.

References

Anupdated meta-analysis. Medicina Clínica, 155(4), 143–151. https://doi.org/10.1016/j.medcli.2020.05.017

Bastos, G. A. N., Azambuja, A. Z. de, Polanczyk, C. A., Gräf, D. D., Zorzo, I. W., Maccari, J. G., Haygert, L. S., Nasi, L. A., Gazzana, M. B., Bessel, M.,

Pitrez, P. M., Oliveira, R. P. de, & Scotta, M. C. (2020). Clinical characteristics and predictors of mechanical ventilation in patients with COVID-

hospitalized in Southern Brazil. Revista Brasileira de Terapia Intensiva, 32(4). https://doi.org/10.5935/0103-507x.20200082

Bosseboeuf, E., Aubry, M., Nhan, T., de Pina, J. J., Rolain, J. M., Raoult, D., & Musso, D. (2018). Azithromycin Inhibits the Replication of Zika Virus. Journal of Antivirals & Antiretrovirals, 10(1). https://doi.org/10.4172/1948-5964.1000173

Carvalho, J. C., Cunha, F., Coutinho, I. A., Loureiro, C., Faria, E., & Bom, A. T. (2021). Hypersensitivity Reactions to Vaccines: Current Evidence and Standards for SARS-CoV-2 Vaccines. Acta Médica Portuguesa, 34(7-8), 541–547. https://doi.org/10.20344/amp.16096

Chen, N., Zhou, M., Dong, X., Qu, J., Gong, F., Han, Y., Qiu, Y., Wang, J., Liu, Y., Wei, Y., Xia, J., Yu, T., Zhang, X., & Zhang, L. (2020). Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet, 395(10223), 507–513.

Recuperado em https://doi.org/10.1016/s0140-6736(20)30211-7

Chen, X., Liao, B., Cheng, L., Peng, X., Xu, X., Li, Y., Hu, T., Li, J., Zhou, X., & Ren, B. (2020). The microbial coinfection in COVID-19. Applied Microbiology and Biotechnology, 104(18), 7777–7785. https://doi.org/10.1007/s00253-020-10814-6

Du Clos, T. W., & Mold, C. (2004). C-reactive protein: an activator of innate immunity and a modulator of adaptive immunity. Immunologic research, 30(3), 261–277. https://doi.org/10.1385/IR:30:3:261

Fontelles, M. J., Simões, M. G., Farias, S. H., & Fontelles, R. G. S. (2009). Metodologia da pesquisa científica: diretrizes para elaboração de um protocolo de pesquisa. Biblioteca Virtual Em Saúde. https://www.google.com/url?sa=t&source=web&rct=j&url=https://pesquisa.bvsalud.org/portal/resource/pt/lil-588477&ved=2ahUKEwjChdWtraz7AhV VrZUCHTCQDNQQFnoECA0QAQ&usg=AOvVaw36OOSgBFFCpIy2M0nKvZup

Gattinoni, L., Chiumello, D., & Rossi, S. (16 C.E.). COVID-19 pneumonia: ARDS or not? Critical Care. Recuperado em https://ccforum.biomedcentral.com/articles/10.1186/s13054-020-02880-z?fbclid=IwAR0LayTy_rv1DeyhF_qMH8URjJafTdgFLiBRoz6OKZUq4JPgb PT125SFqg0

Huttner, B. D., Catho, G., Pano-Pardo, J. R., Pulcini, C., & Schouten, J. (2020). COVID-19: don’t neglect antimicrobial stewardship principles! Clinical Microbiology and Infection, 26(7), 808–810. Recuperado em https://doi.org/10.1016/j.cmi.2020.04.024

Mayara Alves Pinto, J., Cristina Saracini, K., Christian Alves de Lima, L., Pereira de Souza, L., Guerino de Lima, M., & Daiane Biavatti de Oliveira Algeri, E. (2017). Gasometria arterial: aplicações e implicações para a enfermagem. Unirg.edu.br. http://ojs.unirg.edu.br/index.php/2/article/view/1117/pdf

Liu, Y., Yang, Y., Zhang, C., Huang, F., Wang, F., Yuan, J., Wang, Z., Li, J., Li, J., Feng, C., Zhang, Z., Wang, L., Peng, L., Chen, L., Qin, Y., Zhao, D., Tan, S., Yin, L., Xu, J., & Zhou, C. (2020). Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury. Science China Life Sciences, 63(3), 364–374. Recuperado em https://doi.org/10.1007/s11427-020-1643-8

Luisi, F., Gandolfi, T. D., Daudt, A. D., Sanvitto, J. P. Z., Pitrez, P. M., & Pinto, L. A. (2012). Efeito anti-inflamatório dos macrolídeos em doenças pulmonares da infância. Jornal Brasileiro de Pneumologia, 38(6), 786–796. Recuperado em https://doi.org/10.1590/S1806-37132012000600016

Martin, P. da S., Gonçalves, S. L., Goularte, P. do S., Dias, E. P., Leonardi, A. E., Tiezzi, D. G., Gabriel, S. A., & Chin, C. M. (2020). História e Epidemiologia da COVID-19. ULAKES JOURNAL of MEDICINE, 1. http://revistas.unilago.edu.br/index.php/ulakes/article/view/253/232

Miranda, C., Silva, V., Capita, R., Alonso-Calleja, C., Igrejas, G., & Poeta, P. (2020). Implications of antibiotics use during the COVID-19 pandemic: present and future. Journal of Antimicrobial Chemotherapy, 75(12), 3413–3416. Recuperado em https://doi.org/10.1093/jac/dkaa350monitoramento de casos graves: um estudo de revisão / Covid-19 andthe use ofgasometry for themonitoringserious cases: a reviewstudy. BrazilianJournalofDevelopment, 8(4), 23278–23292.

Oliveira, M. F. de. (2011). Manual de Metodologia Cientifica: um manual para realização de pesquisas em administração / Maxwell Ferreira de Oliveira. – Catalão UFG, 2011. 72 p :il. https://pt.scribd.com/document/288474316/Manual-de-Metodologia-Cientifica-Prof-Maxwell

Qu, R., Ling, Y., Zhang, Y. H., Wei, L. Y., Chen, X., Li, X. M., Liu, X. Y., Liu, H. M., Guo, Z., Ren, H., & Wang, Q. (2020). Platelet-to-lymphocyteratio is associated with prognosis in patients with coronavirus disease-19. Journalof medical virology, 92(9), 1533–1541. https://doi.org/10.1002/jmv.25767

Queiroga Cartaxo, M. A., Moreira da Cruz, R. O., Ferreira Dias, R., Câmara Medeiros Parente, R., Yoshimasa Okane, S., Pinheiro, M., Angotti Neto, H., Santos da Silva, R., Correia de Medeiros, A., Diretor-presidente Antônio, D. A., Leite Soares, B., Monteiro Cruz, L., Yoshito Wada, M., Fontana Sutile Tardetti Fantinato, F., Regina Farias Pontes Lucena, A., Filizolla, E., da Silva Ferreira, G., & de Lima, E. (2021). Plano nacional de operacionalização da vacinação contra a covid-19 brasil unido #pátria vacinada. https://www.conasems.org.br/wp-content/uploads/2021/04/PLANONACIONALDEVACINACAOCOVID19_ED06_V3_28.04.pdf. https://doi.org/10.34117/bjdv8n4-037

Ribeiro, A. C., & Carla da Silva André Uehara, S. (10 C.E., January). Hipertensão arterial sistêmica como fator de risco para a forma grave da covid-19:

revisão de escopo. Revista de Saúde Publica. https://scielosp.org/pdf/rsp/2022.v56/20/pt#:~:text=Nesta%20revis%C3%A3o%20de%20escopo%2C%20os, pacientes%20do%20sexo%20feminino28%2C30

Scholz, J. R., Lopes, M. A. C. Q., Saraiva, J. F. K., & Colombo, F. C. (2020). COVID-19, Renin-Angiotensin System, Angiotensin-Converting Enzyme 2, and Nicotine: What is the Interrelation?. COVID-19, Sistema Renina-Angiotensina, Enzima Conversora da Angiotensina 2 e Nicotina: Qual a Inter-Relação?. Arquivos brasileiros de cardiologia, 115(4), 708–711. Recuperado em https://doi.org/10.36660/abc.20200653

Sérgio da Paz Silva Filho, P., James de Sousa Silva, M., José Fortes Júnior, E., opes Rocha, M. M., Amorim Araujo, I., Campelo Soares de Carvalho, I., Messias Esperandio, J. V., Araujo Benoliel Vasconcelos, A. C., Férrer Pompeu, J. G., Sousa Campelo, V. E., Rufino da Silveira Filho, E., Rocha de Paiva, M. L., Monteiro Carvalho, A., Soares Guedes, J. J., Dos Santos Jansen Rodrigues, I. C., da Silva Valente, V., Suênnya de Sousa Pires, A., & Vasconcelos Mesquita, G. (2631). Vacinas contra Coronavírus (COVID-19; SARS-COV-2) no Brasil: um panorama geral Coronavirus vaccines (COVID-19; SARS-COV-2) in Brazil: an overview Vacunas contra el coronavirus (COVID-19; SARS-COV-2) en Brasil: una descripción general Maurício Jammes de Sousa Silva Edmar José Fortes Júnior Eudes Rufino da Silveira Filho Melka Luciana Rocha de Paiva. Research, Societyand Development, 10(8). Recuperado em

https://doi.org/10.33448/rsd-v10i8.17189

Silva, L. O. P., Alves, E. A., & Nogueira, J. M. R. (2021). Uso indiscriminado de antibióticos durante a pandemia: o aumento da resistência bacteriana pós-COVID-19. Revista RBAC, 53(2), 185–186. Recuperado em http://www.rbac.org.br/artigos/uso-indiscriminado-de-antibioticos-durante-pandemia-o-aumento da-resistencia-bacteriana-pos-covid-19/

Silva, T. B. P. dos S., Junior, E. dos S. P., & Andrade, J. N. (2022). Covid-19 e o uso da gasometria para o monitoramento de casos graves: um estudo de revisão / Covid-19 andthe use ofgasometry for the monitoringserious cases: a reviewstudy. BrazilianJournalofDevelopment, 8(4), 23278–23292.

Recuperado em https://doi.org/10.34117/bjdv8n4-037

Sociedade Brasileira de Imunização (SBIM).E quanto à segurança das vacinas Covid-19, o que sabemos? - SBIm. (n.d.). Sbim.org.br. Retrieved November 18, 2022, from https://sbim.org.br/covid-19/75-perguntas-e-respostas-sobre-as-vacinas/vacinas-covid-19-eficacia-seguranca-e-duracao-de-protecao/1509-e-quanto-a-seguranca-das-vacinas-covid-19-o-que-sabemos

Soraya, G. V., &Ulhaq, Z. S. (2020). Crucial laboratoryparameters in COVID-19 diagnosisandprognosis: Anupdated meta-analysis. Medicina Clínica, 155(4), 143–151. Recuperado em https://doi.org/10.1016/j.medcli.2020.05.017

ten-Caten, F., Gonzalez-Dias, P., Castrob, Í., L.T. Ogava, R., n Giddaluru, J., Carlo S. Silva, J., Martinsb, F., N.A. Gonçalves, A., G. Costa-Martins, A., D. Araujo, J., Carolina Viegas, A., Q. Cunha, F., Farskyb, S., A. Bozza, F., S. Levin, A., S. Pannara, P., I. de Silva, T., Minoprioc, P., o Pinheiro da Silvaj, F., & B. Andrade, B. (2021). In-depth analysis of laboratory parameters reveals the interplay between sex, age, and systemic inflammation in individuals with COVID-19. International Journal of Infectious Diseases, 105, 579–587. Recuperado em https://doi.org/10.1016/j.ijid.2021.03.016

Wei, W., Ortwine, J. K., Mang, N. S., Joseph, C., Hall, B. C., & Prokesch, B. C. (2020, June 4). Limited Role for Antibiotics in COVID-19: Scarce Evidence of

Bacterial Coinfection. Papers.ssrn.com. Recuperado em https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3622388

WHO (Word Health Organizacion). Report of the WHO-China Joint Mission on Coronavirus Disease 2019 - 2020.

https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf.

WHO. Preventing the COVID-19 pandemic from causing an antibiotic resistance catastrophe. World Health Organization, Europa, v. 1, n. 1, p. 1-1, 2020. https://www.euro.who.int/ en/health-topics/disease-prevention/antimicrobial-resistance/news/ news/2020/11/preventing-the-covid-19- pandemic-from-causing- an-antibiotic-resistance-catastrophe.

Wu, C.-P., Adhi, F., & Highland, K. (2020). Recognition and management of respiratory co-infection and secondary bacterial pneumonia in patients with COVID-19. Cleveland Clinic Journal of Medicine, 87(11), 659–663. Recuperado em https://doi.org/10.3949/ccjm.87a.ccc015

Zangirolami-Raimundo, J., Echeimberg, J. D. O., & Leone, C. (2018). Research methodology topics: Cross-sectional studies. Journal of Human Growth and Development, 28(3), 356–360. Researchgate. Recuperado de: https://doi.org/10.7322/jhgd.152198

Zhang, J., Dong, X., Cao, Y., Yuan, Y., Yang, Y., Yan, Y., Akdis, C. A., & Gao, Y. (2020). Clinical characteristics of 140 patients infected with SARS‐CoV‐2 in Wuhan, China. Allergy, 75(7). https://doi.org/10.1111/all.14238

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07/12/2022

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CAFÉ, J. F. .; MOURA , N. R. F. .; PIEROTE, G. F. .; SILVA, N. R. .; BACELAR, J. A. .; LACERDA, . M. C. C. .; SILVA, T. P. .; AMORIM, A. . T. .; PORTELA, F. S. . Profile of laboratory tests of patients admitted to an Intensive Care Unit (ICU) with severe forms of COVID-19. Research, Society and Development, [S. l.], v. 11, n. 16, p. e253111638199, 2022. DOI: 10.33448/rsd-v11i16.38199. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/38199. Acesso em: 20 apr. 2024.

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Copyright (c) 2022 Júlia Figueiredo Café; Nattan Rangel Fernandes Moura ; Glenda Farias Pierote; Natiele Ramos Silva; Juliana Abreu Bacelar; Maria Clara Costa Lacerda; Tatielle Pereira Silva; Aline Teixeira Amorim; Fernanda Santos Portela

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