Does vitamin D level have an effect on COVID-19 positivity and COVID-19 related mortality? A retrospective study

Authors

DOI:

https://doi.org/10.47391/JPMA.4593

Abstract

Objective: To explore the possible relationship between vitamin D and coronavirus disease-2019 in an urban population known to have relatively low vitamin D levels.

Method: The retrospective study was conducted in Bursa, Turkey, and comprised data of 30 family health centers from March 1 to December 15, 2020, related to diagnosed inpatients of coronovairus disease-2019. The diagnosis was based on polymerase chain reaction test for severe acute respiratory syndrome coronavirus-2 infection. Vitamin D levels of these patients were obtained from previous records and compared with those without polymerase chain reaction positivity. Vitamin D levels of positive patients who survived were compared with those who died of coronavirus disease-2019. Data was analysed using SPSS 21.

Result: Of the 2,105 patients whose data was retrived, 212(10%) were positive for coronavirus disease-2019, while 1,893(90%) were negative. Among the positive patients, 89(42%) were men and 123(58%) were women. The overall median age was 45 years (Q1-Q3(Q1: first quartile, Q3: third quartile): 35-56 years). Vitamin D level was not significantly different between the positive and negative patients (p>0.05). Among the positive patients, 2(0.9%) patients did not have new admissions to the designated centers and their data was excluded, 206(97.2%) survived and 4(1.9%) died. There was no significant difference in vitamin D levels between those who survived and those who died (p>0.05).

Conclusion: There was no significant relationship found between vitamin D levels and coronavirus disease-2019 infection and related deaths.

Key Words: COVID-19, PCR positivity, SARS-CoV-2 infection, Vitamin D.

Author Biographies

Olgun Goktas, Department of Family Medicine, Uludag University Family Health Center, Bursa, Turkey

Uludag University Family Health Center, Bursa, Turkey

Ilker Ercan, Department of Biostatistics, Uludag University, Bursa, Turkey

Bursa Uluda? University, Faculty of Medicine, Department of Biostatistics, Bursa, Turkey

Canan Ersoy, Department of Internal Medicine, Uludag University, Bursa, Turkey

Uluda? University Faculty of Medicine, Department of Internal Medicine, Division of  Endocrinology and Metabolism, Bursa, Turkey

Arda Uzunoglu, Department of Biostatistics, Uludag University, Health Sciences Institute, Bursa, Turkey

Bursa Uluda? University, Health Sciences Institute, Department of Biostatistics, Bursa, Turkey

Fatma Ezgi Can, Department of Biostatistics, Izmir Katip Celebi University, Izmir, Turkey

?zmir Katip Çelebi University, Faculty of Medicine, Department of Biostatistics, ?zmir, Turkey

Published

2022-08-15

How to Cite

Goktas, O., Ercan, I., Canan Ersoy, Arda Uzunoglu, & Fatma Ezgi Can. (2022). Does vitamin D level have an effect on COVID-19 positivity and COVID-19 related mortality? A retrospective study. Journal of the Pakistan Medical Association, 72(9), 1779–1782. https://doi.org/10.47391/JPMA.4593

Issue

Section

Research Article