ReviewClinical laboratory evaluation of COVID-19
Keywords
SARS-CoV-2
COVID-19
Laboratory diagnosis
Biomarker
Abbreviations
COVID-19
coronavirus disease 2019
SARS-CoV
severe acute respiratory syndrome coronavirus
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
MERS-CoV
middle east respiratory syndrome coronavirus
ACE
angiotensin-converting enzyme
ACE2
angiotensin-converting enzyme 2
TMPRSS2
transmembrane protease serine type 2
ARDS
acute respiratory distress syndrome
RBD
receptor binding domains
NAAT
nucleic acid amplification testing
WHO
world health organization
PCR
polymerase chain reaction
RT-PCR
reverse transcription polymerase chain reaction
qRT-PCR
real-time quantitative reverse transcription polymerase chain reaction
ORF
open-reading frames
LOD
limit of detection
POCT
point-of-care tests
RT-LAMP
reverse transcription loop-mediated isothermal amplification
BLF
bronchoalveolar lavage fluid
RdRp
RNA-dependent RNA polymerase
LRT
lower respiratory tract
Ag-RDT
Antigen-detecting rapid diagnostic test
ELISA
enzyme-linked immunosorbent assay
CLIA
chemiluminescence-immunoassay
IgM
immunoglobulin M
IgG
immunoglobulin G
IgA
immunoglobulin A
FDA
food and drug administration’s
US
United States
EUA
emergency use authorization
ICU
intensive care unit
WBC
white blood cell
NLR
neutrophil–lymphocyte ratio
PLRs
platelet-to-lymphocyte ratios
LDH
lactate dehydrogenase
AST
aspartate aminotransferase
ALT
alanine aminotransferase
CK
creatine kinase
PE
pulmonary embolism
DIC
disseminated intravascular coagulation
FDP
fibrinogen and fibrin degradation products
PT
prothrombin time
APTT
activated partial thromboplastin time
CSS
cytokine storm syndrome
IL-1β
interleukin 1β
IL-2
interleukin 2
IL-2R
interleukin 2R
IL-7
interleukin 7
IL-10
interleukin 10
IL-6
interleukin 6
G-CSF
granulocyte-colony stimulating factor
IFN-α
interferon α
IFN-γ
interferon γ
IP10
induced protein 10
MCP1
monocyte chemoattractant protein 1
MIP-1α
macrophage inflammatory protein-1α
TNF-α
tumor necrosis factor-α
VEGF
vascular endothelial growth factor
TRAIL
TNF related apoptosis inducing ligand
CRP
C-reactive protein
SAA
serum amyloid A protein
PCT
procalcitonin
RAS
renin-angiotensin system
Ang II
angiotensin II
Ang I
angiotensin I
MasR
Mas receptor
AT2R
AT2 receptor
Cited by (0)
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Zhufeng Chen and Wanju Xu contributed equally to this work.
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