感染症学雑誌
Online ISSN : 1884-569X
Print ISSN : 0387-5911
ISSN-L : 0387-5911
症例
鼻炎・副鼻腔炎を併発し,発病からSARS-CoV-2 PCR 検査陰性まで41 日間を要したCOVID-19 肺炎の1 例
山﨑 善隆小坂 充清水 勝利坂口 幸治
著者情報
ジャーナル フリー

2020 年 94 巻 4 号 p. 583-586

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We report the case of a patient with pneumonia caused by the new coronavirus (COVID-19 pneumonia),who contracted the novel coronavirus (SARS-CoV-2) infection on a large cruise ship, and was hospitalized due to fever and cough. The fever resolved immediately after admission, however, a mild cough persisted. Chest CT showed multiple ground-glass opacities in the upper and lower lobes of both lungs. However, we judged that the patient was at a low risk of exacerbation of the disease as he was young, and did not administer any antiviral drugs. Since the subjective symptoms improved, we repeated the SARS-CoV-2 PCR test on day 9 after the onset of the illness, but the result was still positive. As the patient was observed to have sinus stenosis in the left nasal cavity at the time of collection of the nasopharyngeal swab for testing, sinus CT was performed. The findings were suggestive of inflammation of the left nasal mucosa, ethmoid sinusitis,and maxillary sinusitis. It took a long 41 days before we could finally confirm two consecutive negative results of the nasopharyngeal swab PCR test for the novel virus. It has not yet been clarified whether the SARS-CoV2-19 virus can cause rhinitis and/or sinusitis, but from our experience of this case, we believe that SARS-CoV2-19 can colonize already infected nasal mucosa and sinuses for a prolonged period of time. It is necessary to pay attention to this aspect, as it may prolong the disease duration and/or increase the risk of relapse.

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© 2020 一般社団法人 日本感染症学会
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