COVID-19Phospholipid remodeling and its derivatives are associated with COVID-19 severity
Graphical abstract
Key words
COVID-19
lipidomics
phospholipid ratio
LPC 16:1
LPE 18:1
Abbreviations used
APACHE II
Acute Physiology and Chronic Health Evaluation II
AUC
Area under the curve
COVID-19
Coronavirus disease 2019
FDR
False discovery rate
LPC 16:1
1-(9Z-Hexadecenoyl)-sn-glycero-3-phosphocholine
LPC
Lysophosphatidylcholine
LPE 18:1
1-Oleoyl-2-hydroxy-sn-glycero-3-[phospho-l-ethanolamine]
LPE
Lysophosphatidylethanolamine
PC O-
Ether PC
PC
Phosphatidylcholine
PE O-
Ether PE
PE
Phosphatidylethanolamine
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Cited by (0)
The first 3 authors contributed equally to this article and all should be considered first author.
Supported by the National Natural Science Foundation of China (grants 22106108, U1801286, 31770984, 81901634), the Natural Science Foundation of Guangdong Province (2019A1515110407), the Shenzhen Science and Technology Peacock Team Project (KQTD20170331145453160), the China Postdoctoral Science Foundation (2021M690785), the Key Science and Technology Project of Shenzhen (JSGG20200225153031960), and the Retired Experts Program of Guangdong Province (2020A1313030065).
Disclosure of potential conflict of interest: The authors declare that they have no relevant conflicts of interest.
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Deceased.
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