Interrelationship between COVID-19 and diabetes mellitus: a systematic review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i2.12191

Keywords:

COVID-19; Diabetes; Coronavirus; Mechanisms; Infection; Systematic review.

Abstract

Introduction: Individuals with diabetes are at a higher risk of hospitalization and mortality from viral, bacterial and fungal infections. Coronavírus-2019 (COVID-19), caused by severe acute respiratory syndrome coronavírus-2 (SARS-CoV-2), spread rapidly to countries and claimed thousands of lives by December 2020. Notably, in several studies, diabetes is one of the most reported comorbidities in patients with severe COVID-19. Objective: Discuss the influence of diabetes on the prognosis of patients with COVID-19 through a literature review. Methodology: It is a systematic review study. To identify the literature published until December 2020, individual search strategies were applied to the following electronic databases: PubMed, Medline, Lilacs and SciELO. Results: It can be noted that based on the new clinical data obtained from COVID-19 patients, several mechanisms, such as cytokine storm, pulmonary and endothelial dysfunction and hypercoagulation, which can make individuals with diabetes more vulnerable to COVID-19. Epidemiological studies show that poorly controlled diabetes is a risk factor for several infectious diseases. Conclusion: Given the clinical importance of diabetes and the pandemic nature of coronaviruses, understanding how diabetes affects the severity of COVID-19 is critical to the development of public awareness and personalized treatment for individuals affected by the disease.

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Published

03/02/2021

How to Cite

MARINHO, F. P. .; LOYOLA, I. S. de .; MONTEIRO, I. de O. F. .; CASTRO, T. M.; CARVALHO, M. das G. de S.; GARCIA, J. A. D. .; SILVÉRIO, A. C. P. .; SANTOS, G. B. . Interrelationship between COVID-19 and diabetes mellitus: a systematic review . Research, Society and Development, [S. l.], v. 10, n. 2, p. e4810212191, 2021. DOI: 10.33448/rsd-v10i2.12191. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/12191. Acesso em: 18 apr. 2024.

Issue

Vol. 10 No. 2

Section

Review Article

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Copyright (c) 2021 Felipe Pereira Marinho; Isabella Santos de Loyola; Igor de Oliveira Freire Monteiro; Tiffani Marioto Castro; Maria das Graças de Souza Carvalho; José Antonio Dias Garcia; Alessandra Cristina Pupin Silvério; Gérsika Bitencourt Santos

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