Original ResearchFull Report: Basic and Translational—Alimentary TractProlonged Impairment of Short-Chain Fatty Acid and L-Isoleucine Biosynthesis in Gut Microbiome in Patients With COVID-19
Full Report: Basic and Translational—Alimentary Tract
Graphical abstract
Keywords
Coronavirus
Gut Microbiome
Microbial Functions
SCFAs
Abbreviations used in this paper
COVID-19
coronavirus disease 2019
CRP
C-reactive protein
FDR
false discovery rate
IQR
interquartile range
LDH
lactate dehydrogenase
MaAsLin
multivariate analysis by linear models
NT-proBNP
N-terminal B-type natriuretic peptide
PLT
levels of platelet count
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
SCFA
short chain fatty acid
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Conflicts of interest The authors disclose no conflicts.
Funding This study was supported by a donation from Koon Wah Mirror Group and was additionally supported in part by InnoHK, The Government of Hong Kong, Special Administrative Region of the People’s Republic of China.
Data availability Raw sequence data generated for this study are available in the Sequence Read (archive under BioProject accession PRJNA689961;. https://www.ncbi.nlm.nih.gov/bioproject/ PRJNA689961).
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Authors share co-first authorship.
© 2022 by the AGA Institute