Letter to the Editor
Chloroquine and COVID-19: role as a bitter taste receptor agonist?

https://doi.org/10.1016/j.nmni.2021.100843Get rights and content
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Abstract

COVID-19 is a world public health emergency caused by the new coronavirus, SARSCoV-2. Many drugs were repurposed as a treatment for COVID-19 patients including Chloroquine (CQ). CQ is a bitter taste receptor agonist reported to relax the airways suggesting a role in preventing disease severity of COVID-19 patients with asthma.

Keywords

Airway relaxation
asthma
bitter taste receptor agonist
bronchodilation
Chloroquine
COVID-19
SARS-CoV-2
TAS2R

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© 2021 The Author(s). Published by Elsevier Ltd.