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COVID Antworten in den wissenschaftlichen Zeitschriften der Welt


31 Ergebisse       Seite 1

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Elsevier: Bioorganic & Medicinal Chemistry
  Original Artikel Datum Titel Autoren   Alle Autoren
1 [GO] 2025―Nov―29 Discovery of thiosemicarbazone derivatives as promising SARS-CoV-2 Mpro inhibitors by spectroscopy and microscale thermophoresis Xing Xue, Leyao Chen, Miao Zhang, Xiaoyu Chang, Ruiyong Wang
2 [GO] 2025―Mai―23 Synthesis and multitarget inhibitory effect of indole-based ethyl cinnamate derivatives against SARS-CoV-2 Mpro and cathepsins for broad-spectrum anti-coronavirus activity Andrea Citarella, Giulia Sibille, Davide Moi, Alessandro Dimasi, Tommaso Braga, Lorenzo Dal Col, et al. (+10)
3 [GO] 2025―Mai―20 Recent breakthroughs in synthetic small molecules targeting SARS-CoV-2 Mpro from 2022 to 2024 Laura Braconi, Alice Sosic, Letizia Crocetti
4 [GO] 2025―Mai―14 Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 Samuel Desta Guma, Kang Song, Haiguo Sun, Lei Yang, Zhaoyin Zhou, Jin Suo, et al. (+7)
5 [GO] 2025―Mrz―07 Discovery and rational optimization of 2, 2′-((1H-indole-2,3-diyl) bis (thio))diacetamide as novel SARS-CoV-2 RdRp inhibitors Yu Shi, Jianyuan Zhao, Min Li, Liya Wei, Qi Shan, Minghua Wang, et al. (+5)
6 [GO] 2025―Feb―26 Design, synthesis and activity evaluation of 4-(quinoline-2-yl)aniline derivatives as SARS-CoV-2 main protease inhibitors Honglei Bao, Hui Meng, Shilin Gong, Yaguo Gong, Gao Tu, Zhenya Du, et al. (+5)
7 [GO] 2025―Feb―18 Design, synthesis and in vitro validation of bivalent binders of SARS-CoV-2 spike protein: Obeticholic, betulinic and glycyrrhetinic acids as building blocks Martina Pedrini, Luca Pozzi, Francesca Sacchi, Andrea Citarella, Valerio Fasano, Pierfausto Seneci, et al. (+10)
8 [GO] 2025―Feb―04 Rational design and synthesis of pyrazole derivatives as potential SARS-CoV-2 Mpro inhibitors: An integrated approach merging combinatorial chemistry, molecular docking, and deep learning Arthur Antunes Ferrarezi, João Vítor Perez de Souza, Bernard Maigret, Erika Seki Kioshima, Sidnei Moura, Arildo José Braz de Oliveira, et al. (+2)
9 [GO] 2024―Okt―11 Structure-guided design and photochemical synthesis of new carbamo(dithioperoxo)thioates with improved potencies to SARS-CoV-2 3CLpro De-Hang Yin, Jie Xin, Shizhao Chen, Shuai-Shuai Li, Zi-Ying Li, Jin-Xi Meng, et al. (+7)
10 [GO] 2024―Sep―12 Design of inhibitors of SARS-CoV-2 papain-like protease deriving from GRL0617: Structure-activity relationships Lukas Kerti, Vladimir Frecer
11 [GO] 2024―Jul―22 Discovery of macrocyclic covalent inhibitors for severe acute respiratory syndrome coronavirus 2 3CL protease Xiubo Tang, Kai Hou, Xiaowu Chen, Wenyuan Fan, Hao Wu, Changliang Wu, Gong-Xin He
12 [GO] 2024―Apr―18 Molecular basis of N-glycan recognition by pradimicin a and its potential as a SARS-CoV-2 entry inhibitor Yu Nakagawa, Masato Fujii, Nanaka Ito, Makoto Ojika, Dai Akase, Misako Aida, et al. (+5)
13 [GO] 2024―Jan―05 Exploiting high-energy hydration sites for the discovery of potent peptide aldehyde inhibitors of the SARS-CoV-2 main protease with cellular antiviral activity Daniel W. Carney, Abba E. Leffler, Jeffrey A. Bell, Asela S. Chandrasinghe, Cecilia Cheng, Edcon Chang, et al. (+14)
14 [GO] 2023―Nov―11 Identification of Ebselen Derivatives as Novel SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Biological Evaluation, and Structure-Activity Relationships Exploration Heng Zhang, Jing Li, Karoly Toth, Ann E. Tollefson, Lanlan Jing, Shenghua Gao, et al. (+2)
15 [GO] 2023―Okt―12 Mass spectrometric assays monitoring the deubiquitinase activity of the SARS-CoV-2 papain-like protease inform on the basis of substrate selectivity and have utility for substrate identification Lennart Brewitz, H.T. Henry Chan, Petra Lukacik, Claire Strain-Damerell, Martin A. Walsh, Fernanda Duarte, Christopher J. Schofield
16 [GO] 2023―Jan―21 Design, synthesis, docking, and biochemical characterization of non-nucleoside SARS-CoV-2 RdRp inhibitors Nicoletta Brindani, Federico Munafò, Andrea Menichetti, Elisa Donati, Michela Nigro, Giuliana Ottonello, et al. (+2)
17 [GO] 2022―Mai―21 Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors Ting Xu, Jie-Ru Meng, Wanqing Cheng, Jia-Zheng Liu, Junyan Chu, Qian Zhang, et al. (+3)
18 [GO] 2022―Mai―11 Design, synthesis and evaluation of inhibitors of the SARS-CoV-2 nsp3 macrodomain Lavinia M. Sherrill, Elva E. Joya, AnnMarie Walker, Anuradha Roy, Yousef M. Alhammad, Moriama Atobatele, et al. (+9)
19 [GO] 2021―Nov―22 Synthesis and Evaluation of Enantiomers of Hydroxychloroquine Against SARS-CoV-2 in vitro Yong Ni, Jinbiao Liao, Zhenlong Qian, Chunxiu Wu, Xiangyu Zhang, Ji Zhang, et al. (+2)
20 [GO] 2021―Sep―20 A short survey of Dengue protease inhibitor development in the past 6 years (2015-2020) with an emphasis on similarities between DENV and SARS-CoV-2 proteases Sheikh Murtuja, Deepak Shilkar, Biswatrish Sarkar, Barij Nayan Sinha, Venkatesan Jayaprakash
21 [GO] 2021―Sep―14 Enzyme Inhibition as a Potential Therapeutic Strategy to Treat COVID-19 Infection Lukas Paulsson-Habegger, Andrew K. Snabaitis, Stephen P. Wren
22 [GO] 2021―Sep―04 Antiviral Evaluation of Hydroxyethylamine Analogs: Inhibitors of SARS-CoV-2 Main Protease (3CLpro), A Virtual Screening and Simulation Approach Yash Gupta, Sumit Kumar, Samantha E. Zak, Krysten A. Jones, Charu Upadhyay, Neha Sharma, et al. (+8)
23 [GO] 2021―Aug―13 Antiviral fungal metabolites and some insights into their contribution to the current COVID-19 pandemic Jacqueline Aparecida Takahashi, Bianca Vianna Rodrigues Barbosa, Matheus Thomaz Nogueira Silva Lima, Patrícia Gomes Cardoso, Christiane Contigli, Lúcia Pinheiro Santos Pimenta
24 [GO] 2021―Aug―11 Potency and Pharmacokinetics of GS-441524 Derivatives against SARS-CoV-2 Daibao Wei, Tianwen Hu, Yumin Zhang, Wei Zheng, Haitao Xue, Jingshan Shen, et al. (+2)
25 [GO] 2021―Jul―23 Potent antiviral activity of Agrimonia pilosa, Galla rhois, and their components against SARS-CoV-2 Yeong-Geun Lee, Kyung Won Kang, Woojae Hong, Yeon Hwa Kim, Jen Taek Oh, Dae Won Park, et al. (+6)
26 [GO] 2021―Jul―03 Synthetic and computational efforts towards the development of peptidomimetics and small-molecule SARS-CoV 3CLpro inhibitors: a review Abhik Paul, Arnab Sarkar, Sanjukta Saha, Avik Maji, Pritha Janah, Tapan Kumar Maity
27 [GO] 2021―Mrz―26 Identification of SARS-CoV-2 viral entry inhibitors using machine learning and cell-based pseudotyped particle assay Hongmao Sun, Yuhong Wang, Catherine Z. Chen, Miao Xu, Hui Guo, Misha Itkin, et al. (+2)
28 [GO] 2021―Jan―23 Potential inhibitors interacting in Neuropilin-1 to develop an adjuvant drug against COVID-19, by molecular docking José Luis Vique-Sánchez
29 [GO] 2020―Nov―06 Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors Sk. Abdul Amin, Suvankar Banerjee, Kalyan Ghosh, Shovanlal Gayen, Tarun Jha
30 [GO] 2020―Sep―10 COVID-19 therapy: what weapons do we bring into battle? Sinara Mônica Vitalino de Almeida, José Cleberson Santos Soares, Keriolaine Lima dos Santos, Josival Emanuel Ferreira Alves, Amélia Galdino Ribeiro, Íris Trindade Tenório Jacob, et al. (+5)
31 [GO] 2020―Sep―08 Druggable targets from coronaviruses for designing new antiviral drugs Leandro Rocha Silva, Paulo Fernando da Silva Santos-Júnior, Júlia de Andrade Brandão, Letícia Anderson, Ênio José Bassi, João Xavier de Araújo-Júnior, et al. (+2)
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