Emergence of New SARS-CoV2 Omicron Variants after the Change of Surveillance and Control Strategy
Abstract
:1. Introduction
2. Materials and Methods
2.1. Sample Collection
2.2. SNP Methods
2.3. WGS Method
2.4. Classification/Characterization
3. Results
3.1. SNP Characterizations
3.2. WGS Characterizations
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Omicron Lineage | World | Asturias | |||||||
---|---|---|---|---|---|---|---|---|---|
N | Detection Date | Characteristic Mutations | n | Sex Female/Male | Age in Years | Detection Date | Arrival Time * (Days) | Mean of Mutations | |
BA.1 | 471,813 | 2021-04-14 | 43 | 25 | 11/14 | 51 (±28) | 2022-01-08 | 269 | 45 (3.8) |
BA.1.1 | 961,052 | 2021-05-15 | 46 | 33 | 16/17 | 57 (±28) | 2022-01-08 | 238 | 44 (4.2) |
BA.1.1.1 | 60,430 | 2021-11-16 | 45 | 42 | 20/22 | 54 (±27) | 2022-01-08 | 53 | 44 (14.1) |
BA.1.1.14 | 19,390 | 2021-12-03 | 45 | 5 | 2/3 | 46 (±36) | 2022-02-19 | 78 | 46 (0.9) |
BA.1.1.18 | 68,924 | 2021-08-23 | 45 | 1 | 1/- | 38 (n.c.) | 2022-03-01 | 190 | 43 (n.c.) |
BA.1.17 | 61,198 | 2021-11-24 | 44 | 48 | 30/18 | 49 (±28) | 2022-01-05 | 42 | 45 (2.9) |
BA.1.17.2 | 187,655 | 2021-07-10 | 45 | 2 | 1/1 | 29 (±5) | 2022-01-25 | 199 | 43 (0.8) |
BA.1.18 | 54,260 | 2021-11-11 | 44 | 2 | 1/1 | 52 (±16) | 2022-01-21 | 71 | 45 (2.1) |
BA.1.8 | 1051 | 2021-12-08 | 47 | 1 | 1/0 | 2 (n.c.) | 2022-03-02 | 84 | 42 (n.c.) |
BA.2 | 1,013,860 | 2021-08-27 | 50 | 172 | 103/69 | 56 (±25) | 2022-01-15 | 141 | 55 (4.3) |
BA.2.12 | 10,355 | 2021-12-06 | 50 | 11 | 9/2 | 61 (±33) | 2022-02-23 | 79 | 57 (2.1) |
BA.2.18 | 4136 | 2022-01-17 | 49 | 3 | 1/2 | 67 (±19) | 2022-05-11 | 114 | 56 (0.6) |
BA.2.23 | 16,040 | 2021-12-09 | 49 | 1 | -/1 | 43 (n.c.) | 2022-04-26 | 138 | 54 (n.c.) |
BA.2.3 | 73,493 | 2021-12-02 | 52 | 40 | 23/17 | 53 (±30) | 2022-02-02 | 62 | 57 (2.2) |
BA.2.9 | 156,403 | 2021-12-17 | 51 | 29 | 18 | 60 (±23) | 2022-02-16 | 61 | 55 (2.6) |
BA.4 | 2520 | 2022-01-10 | 52 | 1 | 1 | 56 (n.c.) | 2022-05-13 | 123 | 64 (n.c.) |
BA.5 | 2163 | 2022-01-05 | 50 | 10 | 6 | 54 (±18) | 2022-04-25 | 110 | 58 (0.7) |
New Classification | Old Classification | Characteristic Mutations | n | Sex Female/Male | Age in Year | Detection Date | Mean of Mutations |
---|---|---|---|---|---|---|---|
BA.2.56 | BA.2/BA.2.3 | BA.2 + gene_S: L452M | 26 | 12/14 | 69 (±14) | 2022-04-24 | 56 (1.0) |
BA.2.3.5 | BA.2 | BA.2.3 + orf1a_T224I | 26 | 14/12 | 52 (±27) | 2022-02-02 | 56 (2.4) |
BF.1 | BA.2/BA.5 | BA.5 + nsp16_V288F, nsp6_V289L. | 11 | 8/3 | 57 (±18) | 2022-04-25 | 58 (0.5) |
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Alba, J.M.G.; Pérez-Martínez, Z.; Boga, J.A.; Rojo-Alba, S.; de Oña, J.G.; Alvarez-Argüelles, M.E.; Rodríguez, G.M.; Gonzalez, I.C.; González, I.H.; Coto, E.; et al. Emergence of New SARS-CoV2 Omicron Variants after the Change of Surveillance and Control Strategy. Microorganisms 2022, 10, 1954. https://doi.org/10.3390/microorganisms10101954
Alba JMG, Pérez-Martínez Z, Boga JA, Rojo-Alba S, de Oña JG, Alvarez-Argüelles ME, Rodríguez GM, Gonzalez IC, González IH, Coto E, et al. Emergence of New SARS-CoV2 Omicron Variants after the Change of Surveillance and Control Strategy. Microorganisms. 2022; 10(10):1954. https://doi.org/10.3390/microorganisms10101954
Chicago/Turabian StyleAlba, José María González, Zulema Pérez-Martínez, José A. Boga, Susana Rojo-Alba, Juan Gómez de Oña, Marta E. Alvarez-Argüelles, Garbriel Martín Rodríguez, Isabel Costales Gonzalez, Ismael Huerta González, Eliecer Coto, and et al. 2022. "Emergence of New SARS-CoV2 Omicron Variants after the Change of Surveillance and Control Strategy" Microorganisms 10, no. 10: 1954. https://doi.org/10.3390/microorganisms10101954