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Treatment of left main coronary artery thrombus during SARS-CoV-2: early surgical revascularization is key

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Indian Journal of Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause a hypercoagulable state leading to coronary artery thrombosis. The optimal management of this phenomenon has not been well elucidated. We describe a 38-year-old male who developed an ST-elevation myocardial infarction secondary to a left main coronary artery thrombus after SARS-CoV-2. The patient failed anticoagulation and fibrinolysis and developed decompensated heart failure. Ultimately, the patient underwent surgical revascularization, which led to full recovery. This highlights the need for refinement in this population. We recommend that early surgical intervention be considered in patients with ST-elevation myocardial infarction secondary to left main coronary artery thrombus in the setting of SARS-CoV-2.

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No data was used in the preparation of this manuscript.

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Funding

No funding was received to assist with the preparation of this manuscript.

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Authors and Affiliations

  1. Department of Surgery, Pennsylvania State University College of Medicine, Hershey, PA, USA

    Ryan M. Holcomb

  2. Division of Cardiac Surgery, Pennsylvania State University College of Medicine, Hershey, PA, USA

    Abdulrhman S. Elnaggar, Behzad Soleimani & Balakrishnan Mahesh

Authors
  1. Ryan M. Holcomb
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  2. Abdulrhman S. Elnaggar
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  3. Behzad Soleimani
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  4. Balakrishnan Mahesh
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Contributions

RMH: writing and editing; ASE: editing; BS: editing; BM: conceptualization, writing, and editing.

Corresponding author

Correspondence to Ryan M. Holcomb.

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Competing interests

The authors have no relevant financial or non-financial interests to disclose.

Ethics approval

The Pennsylvania State University College of Medicine Institutional Review Board reviewed and granted approval for this study in January 2022.

Consent to participate

Informed consent to publish was obtained from the patient prior to the initiation of this manuscript.

Statement of human and animal rights

The procedures followed in this patient’s case were in accordance with the ethical standards of the Pennsylvania State University College of Medicine Institutional Review Board and with the Helsinki Declaration. No animals were used in this study.

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Holcomb, R.M., Elnaggar, A.S., Soleimani, B. et al. Treatment of left main coronary artery thrombus during SARS-CoV-2: early surgical revascularization is key. Indian J Thorac Cardiovasc Surg 40, 716–718 (2024). https://doi.org/10.1007/s12055-024-01714-9

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  • DOI: https://doi.org/10.1007/s12055-024-01714-9

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