Высокопатогенный грипп Н5: риски формирования нового пандемического штамма

Д. М. Даниленко; А. Б. Комиссаров; А. А. Передерий; А. В. Фадеев; Д. А. Лиознов

doi:10.22625/2072-6732-2023-15-4-14-24

Высокопатогенный грипп Н5: риски формирования нового пандемического штамма

Д. М. Даниленко, А. Б. Комиссаров, А. А. Передерий, А. В. Фадеев, Д. А. Лиознов

https://doi.org/10.22625/2072-6732-2023-15-4-14-24

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Аннотация

В обзоре представлены краткие исторические сведения о высокопатогенном гриппе А подтипа H5. Показаны пути формирования потенциально пандемических вирусов и роль низкопатогенных вирусов гриппа в этом процессе. Отдельно внимание уделяется современному состоянию проблемы – распространению вирусов высокопатогенного гриппа подтипа Н5 на территориях, где он ранее не был зарегистрирован, преодолению межвидового барьера, утрате сезонности в циркуляции гриппа Н5, формированию вариантов вируса, имеющих эволюционное преимущество для репликации в организме млекопитающих и человека. Рассмотрены вопросы вакцинации поголовья домашней птицы как средства для снижения интенсивной циркуляции гриппа и проблемы ее внедрения в глобальном масштабе. Кроме того, обсуждаются риски дальнейшего распространения высокопатогенного гриппа и появления пандемических штаммов.

Ключевые слова

высокопатогенный грипп птиц, изменчивость, потенциально пандемический штамм, риски распространения

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Для цитирования:

Даниленко Д.М., Комиссаров А.Б., Передерий А.А., Фадеев А.В., Лиознов Д.А. Высокопатогенный грипп Н5: риски формирования нового пандемического штамма. Журнал инфектологии. 2023;15(4):14-24. https://doi.org/10.22625/2072-6732-2023-15-4-14-24

For citation:

Danilenko D.M., Komissarov A.B., Perederiy A.A., Fadeyev A.V., Lioznov D.A. Highly pathogenic influenza H5: risks of a new pandemic strain developing. Journal Infectology. 2023;15(4):14-24. (In Russ.) https://doi.org/10.22625/2072-6732-2023-15-4-14-24

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Высокопатогенный грипп Н5: риски формирования нового пандемического штамма

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Высокопатогенный грипп Н5: риски формирования нового пандемического штамма

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