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Original Artikel |
Datum |
Titel |
Autoren Max. 6 Autoren |
| 1 |
[GO] |
2026―Mai―23 |
Ligand-Based Pharmacophore Modeling and Structure-Based Virtual Screening for Identifying Potential Therapeutic Agents Targeting the SARS-CoV-2 Spike Protein-ACE2 Receptor Interaction |
Timoteo Delgado-Maldonado, Gilberto Vargas-Salas, Debasish Bandyopadhyay, Adriana Moreno-Rodríguez, Eyra Ortiz-Pérez, Gildardo Rivera |
| 2 |
[GO] |
2026―Mai―09 |
Inhibitors Targeting SARS-CoV-2 Papain-Like Protease: Screening, Design, Synthesis, and Biological Evaluation |
Elena-Oriana Iuga, Nilu Gone, Mariana Ortiz de Godoy, Gabriel Correa Verissimo, Giovanna de Jesus Agostinetto, Liam Urich, Nadine Krüger, Thales Kronenberger, Rafael Victorio Carvalho Guido, Anthony J. O’Donoghue, Stefan A. Laufer, Thanigaimalai Pillaiyar |
| 3 |
[GO] |
2026―Apr―11 |
2-Phenylquinolines Exhibit Anti-Severe Acute Respiratory Syndrome Coronavirus-2 Activity Through the Nonstructural Protein 13 Helicase Inhibition |
Giada Cernicchi, Maria Giulia Nizi, Roberta Emmolo, Leentje Persoons, Manon Laporte, Dirk Jochmans, Isabella Romeo, Giacomo Pepe, Ciro Milite, Pietro Campiglia, Jacopo Spezzini, Alma Martelli, Simone Brogi, Francesca Esposito, Tommaso Felicetti, Serena Massari, Giuseppe Manfroni, Stefano Sabatini, Gianluca Sbardella, Stefano Alcaro, Johan Neyts, Angela Corona, Enzo Tramontano, Steven De Jonghe, Oriana Tabarrini |
| 4 |
[GO] |
2026―Mrz―08 |
Therapeutic Approaches to Treat SARS-CoV-2 |
Lekhnath Sharma, Neelesh Maheshwari, Nupur Maheshwari, Ghanshyam Teli, Venkatesh Chelvam |
| 5 |
[GO] |
2026―Jan―31 |
Machine Learning-Guided Repositioning of a SARS-CoV-2-Targeting Molecular Series as Cruzain Inhibitors |
Rafael F. Lameiro, Luiz F. Barbosa, Evelin R. Cardoso, Beatriz Siqueira Ho, Felipe Cardoso Prado Martins, Bruna C. de Melo, Fabiana Rosini, Anwar Shamim, Priscila M. Souza, Wellington Falcão de Souza, Carlos A. Montanari |
| 6 |
[GO] |
2025―Nov―23 |
Allosteric Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase Based on
N
,
N′
-Diphenylurea |
Artem Chayka, Matěj Danda, Alžběta Dostálková, Vojtěch Spiwok, Lamija Zijadic, Anna Klimešová, Marina Kapisheva, Michala Zgarbová, Jan Weber, Tomáš Ruml, Michaela Rumlová, Zlatko Janeba |
| 7 |
[GO] |
2025―Mai―05 |
Structure-Activity Relationships of New 1-Aryl-1H-indole Derivatives as SARS-CoV-2 Nsp13 Inhibitors |
Valentina Noemi Madia, Roberta Emmolo, Elisa Patacchini, Donatella Amatore, Stefania Maloccu, Davide Ialongo, Aurora Albano, Giuseppe Ruggieri, Emanuele Cara, Laura Zarbo, Antonella Messore, Riccardo De Santis, Alessandra Amoroso, Florigio Lista, Francesca Esposito, Enzo Tramontano, Angela Corona, Roberto Di Santo, Roberta Costi |
| 8 |
[GO] |
2025―Mrz―11 |
Peptides Corresponding to the Receptor-Binding Domain (RBD) of Several SARS-CoV-2 Variants Of Concern Prevent Recognition of the Human ACE2 Receptor and Consecutive Cell Infections |
Mandy Schwarze, Alexandra Brakel, Ralf Hoffmann, Andor Krizsan |
| 9 |
[GO] |
2024―Sep―11 |
Structural basis for inhibition of the SARS-CoV-2 nsp16 by substrate-based dual site inhibitors |
Gints Kalnins, Laura Rudusa, Anna Bula, Diana Zelencova-Gopejenko, Olga Bobileva, Mihails Sisovs, Kaspars Tars, Aigars Jirgensons, Kristaps Jaudzems, Raitis Bobrovs |
| 10 |
[GO] |
2024―Aug―14 |
Developing Allosteric Inhibitors of SARS-CoV-2 RNA-dependent RNA polymerase |
Artem Chayka, Matěj Danda, Alžběta Dostálková, Vojtěch Spiwok, Anna Klimešová, Marina Kapisheva, Michala Zgarbová, Jan Weber, Tomáš Ruml, Michaela Rumlová, Zlatko Janeba |
| 11 |
[GO] |
2024―Jul―08 |
Discovery of Fluorescent Naturally-occurring Inhibitor of SARS-CoV-2 Main Protease By AIE Fluorescent Probe |
Chong-Jing Zhang, Hao Lin |
| 12 |
[GO] |
2024―Mai―17 |
Front Cover: Identification of Potential Inhibitors of the SARS-CoV-2 NSP13 Helicase via Structure-Based Ligand Design, Molecular Docking and Nonequilibrium Alchemical Simulations (ChemMedChem 10/2024) |
Giorgio Di Paco, Marina Macchiagodena, Piero Procacci |
| 13 |
[GO] |
2024―Mrz―08 |
Identification of Potential inhibitors of the SARS-CoV-2 NSP13 Helicase via Structure-Based Ligand Design, Molecular Docking and Nonequilibrium Alchemical Simulations |
Giorgio Di Paco, Marina Macchiagodena, Piero Procacci |
| 14 |
[GO] |
2023―Mai―30 |
A patent review on SARS coronavirus papain-like protease (PLpro) inhibitors. |
C. S. Brian Chia, Siew Pheng Lim |
| 15 |
[GO] |
2023―Feb―22 |
A critical study on acylating and covalent reversible fragment inhibitors of SARS-CoV-2 main protease targeting the S1-site with pyridine |
Rebekka Wamser, Szymon Pach, Christoph Arkona, Morris Baumgardt, Umer Bin Abdul Aziz, Andreas C. Hocke, Gerhard Wolber, Jörg Rademann |
| 16 |
[GO] |
2022―Okt―03 |
Effects of the 5'-Triphosphate Metabolites of Ribavirin, Sofosbuvir, Vidarabine, and Molnupiravir on CTP Synthase. Implications for Repurposing Antiviral Agents Against SARS-CoV-2 |
Thomas D. Gillis, Stephen L. Bearne |
| 17 |
[GO] |
2022―Sep―27 |
Recent Drug Development and Medicinal Chemistry Approaches for the Treatment of SARS-CoV-2 and Covid-19 |
Arun K Ghosh, Jennifer L. Mishevich, Andrew Mesecar, Hiroaki Mitsuya |
| 18 |
[GO] |
2022―Aug―29 |
Toward a Home Test for COVID 19 Diagnosis: DNA Machine for Amplification-Free SARS-CoV-2 Detection in Clinical Samples |
Ahmed A. ElDeeb, Sofia S. Zablotskaya, Maria S. Rubel, Moustapha A. Y. Nour, Liubov I. Kozlovskaya, Anna A. Shtro, Andrey B. Komissarov, Dmitry M Kolpashchikov |
| 19 |
[GO] |
2022―Jun―20 |
Corrigendum: Promising Therapeutic Approach for SARS-CoV-2 Infections by Using a Rutin-Based Combination Therapy |
Monika Mazik |
| 20 |
[GO] |
2022―Mai―02 |
One Solution for All: Searching for Universal Aptamers for Constantly Mutating Spike Proteins of SARS-CoV-2 |
Jiuxing Li, Zijie Zhang, Ryan Amini, Yingfu Li |
| 21 |
[GO] |
2022―Apr―30 |
Promising therapeutic approach for SARS-CoV-2 infection by using a rutin-based combination therapy |
Monika Mazik |
| 22 |
[GO] |
2022―Feb―21 |
Synthesis and In Vitro Study of Artemisinin/Synthetic Peroxide Based Hybrid Compounds against SARS-CoV-2 and Cancer |
Lars Herrmann, Ivan A. Yaremenko, Aysun Çapcı, Julia Struwe, Dhanir Tailor, Arpit Dheeraj, Jan Hodek, Yulia Yu. Belyakova, Peter Radulov, Jan Weber, Sanjay V. Malhotra, Alexander O. Terent'ev, Lutz Ackermann, Svetlana B. Tsogoeva |
| 23 |
[GO] |
2022―Feb―08 |
Corrigendum: Drug Repurposing for the SARS-CoV-2 Papain-Like Protease |
Chia-Chuan Cho, Shuhua G. Li, Tyler J. Lalonde, Kai S. Yang, Ge Yu, Yuchen Qiao, Shiqing Xu, Wenshe Ray Liu |
| 24 |
[GO] |
2022―Feb―03 |
Synthesis of Dihydrobenzofuro[3,2-b]chromenes as a potential 3CLpro inhibitors of SARS-CoV-2: A molecular docking and dynamics simulation study |
Sudip Gorai, Vivek Junghare, Kshama Kundu, Sowmomita Gharui, Mukesh Kumar, Birija Sankar Patro, Sandip K. Nayak, Saugata Hazra, Soumyaditya Mula |
| 25 |
[GO] |
2022―Jan―27 |
Mass spectrometric assays reveal discrepancies in inhibition profiles for the SARS-CoV-2 papain-like protease |
Lennart Brewitz, Jos J. A. G. Kamps, Petra Lukacik, Claire Strain-Damerell, Yilin Zhao, Anthony Tumber, Tika R. Malla, Allen M. Orville, Martin A. Walsh, Christopher Schofield |
| 26 |
[GO] |
2022―Jan―07 |
Front Cover: MPI8 is Potent against SARS-CoV-2 by Inhibiting Dually and Selectively the SARS-CoV-2 Main Protease and the Host Cathepsin L (ChemMedChem 1/2022) |
Xinyu R. Ma, Yugendar R. Alugubelli, Yuying Ma, Erol C. Vatansever, Danielle A. Scott, Yuchen Qiao, Ge Yu, Shiqing Xu, Wenshe Ray Liu |
| 27 |
[GO] |
2021―Dez―10 |
Corrigendum: New Pyrazine Conjugates: Synthesis, Computational Studies, and Antiviral Properties against SARS-CoV-2 |
Israa A. Seliem, Adel S. Girgis, Yassmin Moatasim, Ahmed Kandeil, Ahmed Mostafa, Mohamed A. Ali, Mohamed S. Bekheit, Siva S. Panda |
| 28 |
[GO] |
2021―Dez―06 |
Front Cover: Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses (ChemMedChem 23/2021) |
Maria Grazia Martina, Ilaria Vicenti, Lisa Bauer, Emmanuele Crespan, Enrico Rango, Adele Boccuto, Noemi Olivieri, Matteo Incerti, Marleen Zwaagstra, Marika Allodi, Simona Bertoni, Elena Dreassi, Maurizio Zazzi, Frank J. M. Kuppeveld, Giovanni Maga, Marco Radi |
| 29 |
[GO] |
2021―Dez―01 |
Structure-Activity Studies Reveal Scope for Optimisation of Ebselen-Type Inhibition of SARS-COV-2 Main Protease |
Siegfried T. D Thun-Hohenstein, Timothy F Suits, Tika R Malla, Anthony Tumber, Lennart Brewitz, Eidarus Salah, Hani Choudhry, Christopher Schofield |
| 30 |
[GO] |
2021―Okt―15 |
A patent review on SARS coronavirus main protease (3CLpro) inhibitors. |
C. S. Brian Chia, Weijun Xu, Pearly Shuyi Ng |
| 31 |
[GO] |
2021―Aug―23 |
Drug Repurposing for the SARS-CoV-2 Papain-Like Protease |
Wenshe Liu, Chia-Chuan Cho, Shuhua G. Li, Tyler J. Lalonde, Kai S. Yang, Ge Yu, Yuchen Qiao, Shiqing Xu |
| 32 |
[GO] |
2021―Aug―12 |
Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus and Human Rhinoviruses |
Maria Grazia Martina, Ilaria Vicenti, Lisa Bauer, Emmanuele Crespan, Enrico Rango, Adele Boccuto, Noemi Olivieri, Matteo Incerti, Marleen Zwaagstra, Marika Allodi, simona bertoni, Elena Dreassi, Maurizio Zazzi, Frank J. M. van Kuppeveld, Giovanni Maga, Marco Radi |
| 33 |
[GO] |
2021―Aug―05 |
New pyrazine conjugates: Synthesis, computational studies, and antiviral properties against SARS-CoV-2 |
Israa A. Seliem, Adel S. Girgis, Yassmin Moatasim, Ahmed Kandeil, Ahmed Mostafa, Mohamed A. Ali, Mohamed S. Bekheit, Siva S Panda |
| 34 |
[GO] |
2021―Jul―09 |
MPI8 is Potent Against SARS-CoV-2 by Inhibiting Dually and Selectively the SARS-CoV-2 Main Protease and the Host Cathepsin L |
Wenshe Liu, R. Xinyu, Yugendar R. Alugubelli, Yuying Ma, Erol C. Vantasever, Danielle A. Scott, Yuchen Qiao, Ge Yu, Shiqing Xu |
| 35 |
[GO] |
2021―Jul―06 |
Front Cover: Inspecting the Mechanism of Fragment Hits Binding on SARS-CoV-2 M
pro
by Using Supervised Molecular Dynamics (SuMD) Simulations (ChemMedChem 13/2021) |
Maicol Bissaro, Giovanni Bolcato, Matteo Pavan, Davide Bassani, Mattia Sturlese, Stefano Moro |
| 36 |
[GO] |
2021―Jun―18 |
In silico characterization of masitinib interaction with SARS-CoV-2 main protease |
Ulises Martínez-Ortega, Diego I. Figueroa-Figueroa, Francisco Hernández-Luis, Rodrigo Aguayo-Ortiz |
| 37 |
[GO] |
2021―Jun―01 |
Poly-L-lysine Glycoconjugates Inhibit DC-SIGN-mediated Attachment of Pandemic Viruses |
Beat Ernst, Jonathan Cramer, Butrint Aliu, Xiaohua Jiang, Timothy Sharpe, Lijuan Pang, Adrian Hadorn, Said Rabbani |
| 38 |
[GO] |
2021―Apr―03 |
Science’s response to CoVID-19 |
Yimon Aye, Marcus Long |
| 39 |
[GO] |
2021―Apr―02 |
Inspecting the mechanism of fragment hit binding on SARS-CoV-2 Mpro by using supervised molecular dynamics (SuMD) simulations. |
Maicol Bissaro, Giovanni Bolcato, Matteo Pavan, Davide Bassani, Mattia Sturlese, Stefano Moro |
| 40 |
[GO] |
2021―Jan―22 |
Front Cover: Structure-Activity Relationships of Benzamides and Isoindolines Designed as SARS-CoV Protease Inhibitors Effective against SARS-CoV-2 (2/2021) |
Armin Welker, Christian Kersten, Christin Müller, Ramakanth Madhugiri, Collin Zimmer, Patrick Müller, Robert Zimmermann, Stefan Hammerschmidt, Hannah Maus, John Ziebuhr, Christoph Sotriffer, Tanja Schirmeister |
| 41 |
[GO] |
2020―Dez―22 |
Action of dipeptidyl peptidase-4 inhibitors on SARS-CoV-2 main protease |
Thomas Klein, Herbert Nar, Gisela Schnapp, Oliver Hucke, Timothy C Hardman |
| 42 |
[GO] |
2020―Dez―07 |
A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors |
Wenshe Liu, Kai Yang, Xinyu Ma, Yuying Ma, Yugendar Alugubelli, Danielle Scott, Erol vatansever, Aleksandra Drelich, Banumathi Sankaran, Zhi Geng, Lauren Blankenship, Hannah Ward, Yan Sheng, Jason Hsu, Kaci Kratch, Baoyu Zhao, Hamed Hayatshahi, Jin Liu, Pingwei Li, Carol Fierke, Chien-Te Tseng, Shiqing Xu |
| 43 |
[GO] |
2020―Sep―16 |
SAR of novel benzamides and isoindolines, designed as SARS-CoV protease inhibitors - effective against SARS-CoV-2 |
Armin Welker, Christian Kersten, Christin Müller, Ramakanth Madhugiri, Collin Zimmer, Patrick Müller, Robert Alexander Zimmermann, Stefan Hammerschmidt, Hannah Maus, John Ziebuhr, Christoph Sotriffer, Tanja Schirmeister |
| 44 |
[GO] |
2020―Jul―23 |
Targeting SARS-CoV-2 RBD interface: a supervised computational data-driven approach to identify potential modulators |
Maria Rita Gulotta, Jessica Lombino, Ugo Perricone, Giada De Simone, Nedra Mekni, Maria De Rosa, Patrizia Diana, Alessandro Padova |
| 45 |
[GO] |
2020―Jul―14 |
ACE2, the Receptor that Enables the Infection by SARS-CoV-2: Biochemistry, Structure, Allostery and Evaluation of the Potential Development of ACE2 Modulators |
Lissy Z.F. Gross, Mariana Sacerdoti, Albrecht Piiper, Stefan Zeuzem, Alejandro E. Leroux, Ricardo M. Biondi |
| 46 |
[GO] |
2020―Apr―23 |
Drug Development and Medicinal Chemistry Efforts Toward SARS-Coronavirus and Covid-19 Therapeutics |
Arun K Ghosh, Margherita Brindisi, Dana Shahabi, Mackenzie E. Chapman, Andrew D. Mesecar |
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