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Original Artikel |
Datum |
Titel |
Autoren Max. 6 Autoren |
| 1 |
[GO] |
2026―Jul―13 |
Novel Compounds as SARS-CoV-2-Related 3C-Like Protease Inhibitors for Treating Coronavirus Infections |
Ram W. Sabnis |
| 2 |
[GO] |
2026―Jun―19 |
Novel Compounds for Inhibiting Viral Replication and Treating and/or Preventing Coronavirus Infections |
Ram W. Sabnis |
| 3 |
[GO] |
2026―Jun―16 |
Novel Compounds as SARS-CoV-2 Main Protease Inhibitors for Treating Viral Infections, in particular, Coronavirus Infections |
Ram W. Sabnis |
| 4 |
[GO] |
2026―Jun―09 |
Novel Compounds as SARS-CoV-2 Main Protease Inhibitors for Treating Viral Infections, in particular, Coronavirus Infections |
Ram W. Sabnis |
| 5 |
[GO] |
2026―Mai―06 |
Novel Competitive, Nonpeptidic, SARS-CoV-2 M
pro
Inhibitors with Improved Solubility |
Zafer Sahin, Mario Rivera, Yanli Yang, Ken Liu, Goknil P. C. Sahin, John Bacsa, Stephen C. Pelly, Dennis C. Liotta |
| 6 |
[GO] |
2026―Mrz―04 |
Ugi-Tetrazole-Derived α-Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV-2 3CLpro |
Robin van der Straat, Rick Oerlemans, Yingying Cong, Jeffrey Boxma, Radu G. Bulai, Clàudia Río-Bergé, Lizbé Koekemoer, Tryfon Zarganes Tzitzikas, Zhirui Guan, Peter George Marples, Fulvio Reggiori, Matthew Groves, Alexander Dömling |
| 7 |
[GO] |
2025―Okt―30 |
Targeting the S1′ Pocket of SARS-CoV-2 Papain-Like Protease Yields Highly Potent Inhibitors |
Dnyaneshwar N. Garad, Xin Li, Teck Khiang Chua, Bala Krishna Moku, Chandra Bhushan Mishra, Yongcheng Song |
| 8 |
[GO] |
2025―Sep―25 |
Identification and Exploration of a Series of SARS-Cov-2 MPro Cyano-Based Inhibitors Revealing Ortho-Substitution Effects within the P3 Biphenyl Group |
Emma Clyde-Allen, Mikołaj Zmudzinski, Mohammad Afsar, Ciyana James, Anindita Nayak, Digant Nayak, Priscila dos Santos Bury, Dirk Jochmans, Johann Neyts, Christopher J. Scott, Shaun K. Olsen, Marcin Drag, Rich Williams |
| 9 |
[GO] |
2025―Sep―16 |
Structure-Guided Temporin L Analogs Development to Inhibit the Main Protease of SARS-CoV-2 |
James Stewart, Ruoqing Jia, Md Ackas Ali, Blaise Williams, Kaylee Stone, Ryan Faddis, Md. Shahadat Hossain, Andrew C. McShan, Mohammed Akhter Hossain, Mohammad A. Halim |
| 10 |
[GO] |
2025―Sep―05 |
Design and Synthesis of Pyrazoline Inhibitors of SARS-CoV-2 NSP14 |
Elliott B. Smyth, João P. Pisco, Kristian Birchall, Nicole S. Upfold, Arvind H. Patel, Richard Foster, Jonathan M. Large |
| 11 |
[GO] |
2025―Aug―15 |
Discovery of Novel Isofunctional SARS-CoV-2 NSP14 RNA Cap Methyltransferase Inhibitors by Structure-Based Virtual Screening |
Cindy Meyer, Mayako Michino, David J. Huggins, Aitor Garzia, Jada A. Davis, Michael W. Miller, Nigel Liverton, Hans-Heinrich Hoffmann, J. Fraser Glickman, Julius Nitsche, Oleg Ganichkin, Stefan Steinbacher, Charles M. Rice, Peter T. Meinke, Thomas Tuschl |
| 12 |
[GO] |
2025―Apr―14 |
Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors |
Liuyan Hu, Zhi Zhao, Shujing Zhang, Lei Yang, Wenjie Cui, Tianwen Hu, Jin Suo, Haiguo Sun, Qiumeng Zhang, Leike Zhang, Weiliang Zhu, Zhijian Xu, Yumin Zhang, Xiangrui Jiang, Yan Zhang, Jingshan Shen |
| 13 |
[GO] |
2025―Mrz―17 |
Design, Synthesis, Evaluation, and Molecular Dynamics Simulation of SARS-CoV-2 Mpro Inhibitors |
Qinghua Yang, Keli Zong, Xu Zhao, Fenghua Zhang, Fei Li, Xingzhou Li |
| 14 |
[GO] |
2024―Dez―02 |
Discovery of Non-Covalent Inhibitors for SARS-CoV-2 PLpro: Integrating Virtual Screening, Synthesis, and Experimental Validation |
Bruna K. P. Sousa, Melina Mottin, Donald Seanego, Christopher D. Jurisch, Beatriz S. A. Rodrigues, Verônica L. S. da Silva, Milene Aparecida Andrade, Gilberto S. Morais, Diogo F. Boerin, Thamires Q. Froes, Flávia Nader Motta, M. Cristina Nonato, Izabela D. M. Bastos, Kelly Chibale, Richard K. Gessner, Carolina Horta Andrade |
| 15 |
[GO] |
2024―Nov―15 |
Pyrrolidines as Main Protease Inhibitors for Treating Viral Infections, in Particular, Coronavirus Infections |
Ram W. Sabnis |
| 16 |
[GO] |
2024―Nov―03 |
Peptide Aldehydes Incorporating Thiazol-4-yl Alanine Are Potent In Vitro Inhibitors of SARS-CoV-2 Main Protease |
Jenson R. Feys, Kyle Edwards, Michael A. Joyce, Holly A. Saffran, Justin A. Shields, Kassandra Garcia, D. Lorne Tyrrell, Conrad Fischer |
| 17 |
[GO] |
2024―Okt―15 |
Novel Papain-Like Protease Inhibitors for Treating Viral Infections, in Particular Coronavirus Infections |
Ram W. Sabnis |
| 18 |
[GO] |
2024―Jul―23 |
Novel Papain-Like Protease Inhibitors for Treating Viral Infections, in particular, Coronavirus Infections |
Ram W. Sabnis |
| 19 |
[GO] |
2024―Jul―23 |
Fragment-Based Screen of SARS-CoV-2 Papain-like Protease (PLpro) |
Ashley J. Taylor, Kangsa Amporndanai, Tyson A. Rietz, Bin Zhao, Anusha Thiruvaipati, Qiangqiang Wei, Taylor M. South, Mackenzie M. Crow, Chideraa Apakama, John L. Sensintaffar, Jason Phan, Taekyu Lee, Stephen W. Fesik |
| 20 |
[GO] |
2024―Mai―20 |
SARS-CoV-2 Main Protease Inhibitors That Leverage Unique Interactions with the Solvent Exposed S3 Site of the Enzyme |
Lauren R. Blankenship, Kai S. Yang, Veerabhadra R. Vulupala, Yugendar R. Alugubelli, Kaustav Khatua, Demonta Coleman, Xinyu R. Ma, Banumathi Sankaran, Chia-Chuan D. Cho, Yuying Ma, Benjamin W. Neuman, Shiqing Xu, Wenshe Ray Liu |
| 21 |
[GO] |
2024―Mrz―14 |
Chemical Space Profiling of SARS-CoV-2 PLpro Using DNA-Encoded Focused Libraries |
Xudong Wang, Ying Zhu, Qingyi Zhao, Weiwei Lu, Yechun Xu, Hangchen Hu, Xiaojie Lu |
| 22 |
[GO] |
2024―Jan―10 |
Development of a GC-376 Based Peptidomimetic PROTAC as a Degrader of 3-Chymotrypsin-like Protease of SARS-CoV-2 |
Deborah Grifagni, Elena Lenci, Alessia De Santis, Andrea Orsetti, Carlo Giorgio Barracchia, Filomena Tedesco, Raffaele Bellini Puglielli, Francesca Lucarelli, Angela Lauriola, Michael Assfalg, Francesca Cantini, Vito Calderone, Daniele Guardavaccaro, Andrea Trabocchi, Mariapina D’Onofrio, Simone Ciofi-Baffoni |
| 23 |
[GO] |
2023―Nov―20 |
Conformationally Restricted Analogues of α-Galactosylceramide as Adjuvant in COVID-19 Subunit Vaccine |
Xing Hu, Mao-Ying Xian, Xi-Feng Wang, Guo-Qing Zou, Rui Luo, Hao Peng, Zheng Liu |
| 24 |
[GO] |
2023―Okt―06 |
Protease Inhibitors for Treating or Preventing Coronavirus Infection |
Ram W. Sabnis |
| 25 |
[GO] |
2023―Sep―29 |
Heparan Sulfate-Mimicking Glycopolymers Bind SARS-CoV-2 Spike Protein in a Length- and Sulfation Pattern-Dependent Manner |
Hawau Abdulsalam, Jiayi Li, Ravi S. Loka, Eric T. Sletten, Hien M. Nguyen |
| 26 |
[GO] |
2023―Sep―28 |
Design and Optimization of Novel Competitive, Non-peptidic, SARS-CoV-2 Mpro Inhibitors |
Leon Jacobs, Aletta van der Westhuyzen, Nicole Pribut, Zackery W. Dentmon, Dan Cui, Michael P. D’Erasmo, Perry W. Bartsch, Ken Liu, Robert M. Cox, Sujay F. Greenlund, Richard K. Plemper, Deborah Mitchell, Joshua Marlow, Meghan K. Andrews, Rebecca E. Krueger, Zachary M. Sticher, Alexander A. Kolykhalov, Michael G. Natchus, Bin Zhou, Stephen C. Pelly, Dennis C. Liotta |
| 27 |
[GO] |
2023―Aug―10 |
Novel Compounds for Preventing SARS-CoV-2 Viral Replication and Treating COVID-19 |
Ram W. Sabnis |
| 28 |
[GO] |
2023―Mai―11 |
Discovery of Small Molecules Targeting the Frameshifting Element RNA in SARS-CoV-2 Viral Genome |
Mo Yang, Feyisola P. Olatunji, Curran Rhodes, Sumirtha Balaratnam, Kara Dunne-Dombrink, Srinath Seshadri, Xiao Liang, Christopher P. Jones, Stuart F. J. Le Grice, Adrian R. Ferré-D’Amaré, John S. Schneekloth |
| 29 |
[GO] |
2022―Aug―19 |
Oral Nonpeptidic, Noncovalent Triazine Coronavirus Main Protease Inhibitors for Treating COVID-19 |
C. S. Brian Chia, Masafumi Inoue |
| 30 |
[GO] |
2022―Aug―08 |
Novel Coronavirus Main Protease Di- and Tripeptide Inhibitors for Treating COVID-19 |
C. S. Brian Chia, Yi Yang See |
| 31 |
[GO] |
2022―Jul―22 |
Bisubstate Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 Nsp14 Methyltransferase |
Eunkyung Jung, Ruben Soto-Acosta, Jiashu Xie, Daniel J. Wilson, Christine D. Dreis, Ryuichi Majima, Tiffany C. Edwards, Robert J. Geraghty, Liqiang Chen |
| 32 |
[GO] |
2022―Jul―19 |
A Warhead Substitution Study on the Coronavirus Main Protease Inhibitor Nirmatrelvir |
Subramanyam Vankadara, Monique Danielle Dawson, Jia Yi Fong, Qin Yao Oh, Qi An Ang, Boping Liu, Hong Yun Chang, Judice Koh, Xiaoying Koh, Qian Wen Tan, Joma Joy, Cheng San Brian Chia |
| 33 |
[GO] |
2022―Jun―06 |
SARS-CoV-2: Novel Therapeutic Approaches for Diagnosis and Treatment |
Robert B. Kargbo |
| 34 |
[GO] |
2022―Mai―27 |
Novel Halomethylketone Azadipeptides for Treating COVID-19 |
C. S. Brian Chia, Yi Yang See |
| 35 |
[GO] |
2022―Mrz―25 |
How a Blockchain Approach Can Improve Data Reliability in the COVID-19 Pandemic |
Pietro Cozzini, Federica Agosta, Greta Dolcetti, Gianfranco Righi |
| 36 |
[GO] |
2022―Feb―21 |
Phosphoramidate Prodrugs Continue to Deliver, The Journey of Remdesivir (GS-5734) from RSV to SARS-CoV-2 |
Richard L. Mackman |
| 37 |
[GO] |
2022―Feb―03 |
Novel Nitrile Peptidomimetics for Treating COVID-19 |
C. S. Brian Chia |
| 38 |
[GO] |
2021―Nov―18 |
Novel Compounds for Preventing SARS-CoV-2 Viral Replication and Treating COVID-19 |
Ram W. Sabnis |
| 39 |
[GO] |
2021―Okt―13 |
Expression of Concern for “Molecular Biology Clues Portray SARS-CoV-2 as a Gain-of-Function Laboratory Manipulation of Bat CoV RaTG13” |
Dennis Liotta |
| 40 |
[GO] |
2021―Okt―09 |
On the Selectivity of Heparan Sulfate Recognition by SARS-CoV-2 Spike Glycoprotein |
John E. Chittum, Nehru Viji Sankaranarayanan, Connor P. O’Hara, Umesh R. Desai |
| 41 |
[GO] |
2021―Sep―29 |
Design and Evaluation of Bispidine-Based SARS-CoV-2 Main Protease Inhibitors |
Dmitriy Shcherbakov, Dmitriy Baev, Mikhail Kalinin, Alexander Dalinger, Varvara Chirkova, Svetlana Belenkaya, Aleksei Khvostov, Dmitry Krut’ko, Aleksei Medved’ko, Ekaterina Volosnikova, Elena Sharlaeva, Daniil Shanshin, Tatyana Tolstikova, Olga Yarovaya, Rinat Maksyutov, Nariman Salakhutdinov, Sergey Vatsadze |
| 42 |
[GO] |
2021―Jul―28 |
Discovery of Small Molecule Entry Inhibitors Targeting the Fusion Peptide of SARS-CoV-2 Spike Protein |
Xin Hu, Catherine Z. Chen, Miao Xu, Zongyi Hu, Hui Guo, Zina Itkin, Paul Shinn, Parker Ivin, Madeleine Leek, T. Jake Liang, Min Shen, Wei Zheng, Matthew D. Hall |
| 43 |
[GO] |
2021―Jul―14 |
Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency |
Chun-Hui Zhang, Krasimir A. Spasov, Raquel A. Reilly, Klarissa Hollander, Elizabeth A. Stone, Joseph A. Ippolito, Maria-Elena Liosi, Maya G. Deshmukh, Julian Tirado-Rives, Shuo Zhang, Zhuobin Liang, Scott J. Miller, Farren Isaacs, Brett D. Lindenbach, Karen S. Anderson, William L. Jorgensen |
| 44 |
[GO] |
2021―Jun―09 |
Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate |
Olga Bobiļeva, Raitis Bobrovs, Iveta Kaņepe, Liene Patetko, Gints Kalniņš, Mihails Šišovs, Anna L. Bula, Solveiga Gri̅nberga, Ma̅rtiņš Borodušķis, Anna Ramata-Stunda, Nils Rostoks, Aigars Jirgensons, Kaspars Ta̅rs, Kristaps Jaudzems |
| 45 |
[GO] |
2021―Mai―27 |
Molecular Biology Clues Portray SARS-CoV-2 as a Gain-of-Function Laboratory Manipulation of Bat CoV RaTG13 |
Ariel Fernández |
| 46 |
[GO] |
2021―Mrz―29 |
Intriguing Antiviral Modified Nucleosides: A Retrospective View into the Future Treatment of COVID-19 |
Ei-ichi Ami, Hiroshi Ohrui |
| 47 |
[GO] |
2021―Mrz―17 |
Structural Insights into Plasticity and Discovery of Remdesivir Metabolite GS-441524 Binding in SARS-CoV-2 Macrodomain |
Xiaomin Ni, Martin Schröder, Vincent Olieric, May E. Sharpe, Victor Hernandez-Olmos, Ewgenij Proschak, Daniel Merk, Stefan Knapp, Apirat Chaikuad |
| 48 |
[GO] |
2020―Dez―10 |
Influence of 4′-Substitution on the Activity of Gemcitabine and Its ProTide Against VZV and SARS-CoV-2 |
Zihua Zheng, Elisabetta Groaz, Robert Snoeck, Steven De Jonghe, Piet Herdewijn, Graciela Andrei |
| 49 |
[GO] |
2020―Nov―12 |
Targeted Disassembling of SARS-CoV-2 as It Gets Ready for Cell Penetration |
Ariel Fernández |
| 50 |
[GO] |
2020―Okt―25 |
Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2 |
Mohammad M. Ghahremanpour, Julian Tirado-Rives, Maya Deshmukh, Joseph A. Ippolito, Chun-Hui Zhang, Israel Cabeza de Vaca, Maria-Elena Liosi, Karen S. Anderson, William L. Jorgensen |
| 51 |
[GO] |
2020―Aug―17 |
Structural Impact of Mutation D614G in SARS-CoV-2 Spike Protein: Enhanced Infectivity and Therapeutic Opportunity |
Ariel Fernández |
| 52 |
[GO] |
2020―Aug―10 |
Striking Similarities between CDRs in Some mAbs That Neutralize COVID-19 |
Tianxiong Mi, Kevin Burgess |
| 53 |
[GO] |
2020―Jun―23 |
Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment |
Victoria C. Yan, Florian L. Muller |
| 54 |
[GO] |
2020―Mai―18 |
Blocking Coronavirus 19 Infection via the SARS-CoV-2 Spike Protein: Initial Steps |
Jonathan Whisenant, Kevin Burgess |
| 55 |
[GO] |
2020―Mai―08 |
A Role for Metal-Based Drugs in Fighting Covid-19 Infection? The Case of Auranofin |
Tiziano Marzo, Luigi Messori |
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